A Study of Response Inhibition in Bipolar Mania Background

Authors: [1] Mohit Kumar [2] Basudeb Das [3] Sanjay Kumar [4] Masood Maqbool [5] Satyam Sharma

Pages: 64-68

Abstract:

Background: It is largely accepted that response inhibition plays a key role in bipolar disorder. However, the effect of specific role played by various sub-facets of response inhibition remains largely unknown. Objective: The present study aims to see various sub-components of response inhibition in patients diagnosed with BPAD current episode manic type. Method: Purposive sampling was used to select 20 patients with diagnosis of BPAD current episode manic type (based on ICD10 DCR) (group 1) from a tertiary care hospital. Another 20 normal healthy subjects (group 2) were taken from accompanying person on the score of less than 3 in GHQ-12. Both the groups were matched on age, sex and education level obtained through initial assessment on socio-demographic clinical data sheet. All the subjects (n=40) were assessed using Stroop Color and Word Test and Wisconsin Card Sorting Test and Sidedness Bias Schedule on both the groups. The collected data were analysed by using probability statistics. Results:There was a statistically significant difference between group 1 and group 2 on measures of Perseverative responses, Percent perseverative responses, Perseverative errors, Percent perseverative errors in WCST. On Stroop Test, Word Score (W), Color Score (C), Color- Word Score (CW) and Trails to complete first category. Conclusion:The findings of this study suggest that response inhibition more present in patients with BPAD than normal subjects